APD/PDL in vSphere 6 with VMAX and VPLEX

Recently I have seen a number of internal emails here at EMC asking about our recommendations around All Paths Dead (APD) and Permanent Device Loss (PDL) in vSphere 6 on our storage arrays - mostly VPLEX to be specific.  There have been significant changes in APD/PDL in vSphere 6 which is why the questions are...